{"id":12212,"date":"2022-03-07T12:58:00","date_gmt":"2022-03-07T07:28:00","guid":{"rendered":"https:\/\/www.wockhardthospitals.com\/?p=8962"},"modified":"2022-03-07T12:58:00","modified_gmt":"2022-03-07T07:28:00","slug":"how-an-artificial-pancreas-can-be-crucial-for-diabetic-patients","status":"publish","type":"post","link":"https:\/\/wockhardthospitals.com\/international-patients\/diabetes\/how-an-artificial-pancreas-can-be-crucial-for-diabetic-patients\/","title":{"rendered":"How an Artificial Pancreas Can Be Crucial for Diabetic Patients"},"content":{"rendered":"\n<\/p>\n<p>The World Health Organization (WHO) describes&nbsp;Diabetes as a chronic metabolic disease&nbsp;characterized by elevated blood sugar levels (or&nbsp;blood sugar<b>),<\/b> which over time can cause severe damage to the heart, blood vessels,&nbsp;eyes, kidneys and nerves. It also states that approximately 422 million people worldwide have diabetes, most of whom live in low- and middle-income countries, and that 1.5 million deaths are directly attributed to diabetes each year.<\/p>\n<p>\n\n\n\n<p>Type 1 diabetes is an autoimmune disease in which the pancreas cannot produce enough insulin while at&nbsp;<a href=\"https:\/\/www.wockhardthospitals.com\/articles\/diabetes\/type-2-diabetes-symptoms-treatment\/\">Type 2 diabetes, <\/a>the body develops insulin resistance, resulting in abnormally high blood sugar levels. As such many&nbsp;diabetic patients&nbsp;life depends on insulin treatment, which can be given by injection or pump, to keep their blood sugar levels under control.<\/p>\n\n\n\n<p>But a new technology automated insulin delivery is attempting to mimic the role of the pancreas, paving the way for breakthrough methods of <a href=\"https:\/\/www.wockhardthospitals.com\/speciality\/diabetology\/\">diabetes surgery<\/a> and its many manifestations. Also called artificial pancreas (AP) or closed-loop systems, the technology combines&nbsp;diabetes&nbsp;Devices, namely an insulin pump connected to a continuous glucose monitor (CGM) and a smartphone program. While insulin pumps have been used since the 1980s to mimic the secretion of a healthy pancreas for patients with <a href=\"https:\/\/www.wockhardthospitals.com\/articles\/diabetes\/type-1-diabetes-symptoms-treatment\/\">type 1 diabetes,<\/a> \u201cthese have to be done manually multiple times a day and therefore have not lived up to expectations,\u201d said Dr. Jothydev Kesavadev.<\/p>\n\n\n\n<\/p>\n<p>However, the artificial pancreas automatically monitors blood sugar levels, calculates and dispenses the amount of insulin needed at different times of the day. This system helps control blood sugar levels and makes it easier for people to keep them in range.<\/p>\n<p>\n\n\n\n<\/p>\n<h2>What is AP and How Does it Work?<\/h2><p><br>\u201cAP consists of three parts \u2013 glucose sensor, program and pump. Continuous glucose monitor (CGM) tracks blood glucose levels every few minutes using a tiny sensor placed under the skin and wirelessly sending the information to a program. The sensor sends the necessary information to the smartphone or an insulin infusion pump. Based on the reading, the insulin pump then delivers small doses of insulin throughout the day when blood glucose is above the target range,\u201d said Dr. David Chandy.<\/p>\n<p>\n\n\n\n<\/p>\n<p>\u201cYou know how much insulin you need and the insulin infusion pump gets a signal when insulin needs to be delivered. The insulin infusion pump then delivers the required insulin. However, values vary with expert guidance,\u201d said Dr. Pritam Moon, Medical Specialist and Diabetologist, Wockhardt Hospital Mira Road.<\/p>\n<p>\n\n\n\n<\/p>\n<p>The Predictive Suspend system calculates blood glucose levels and stops insulin delivery before your&nbsp;blood sugar levels&nbsp;becomes too low. \u201cStopping insulin delivery at the right moment can help a person with type 1 diabetes avoid low blood sugar or hypoglycemia, a condition in which a person\u2019s blood glucose level is below the target range,\u201d said Dr. chandy<\/p>\n<p>\n\n\n\n<\/p>\n<p>The gap, however, was in automating insulin delivery \u2014 which \u201cused to be a dream,\u201d said Dr. Kesavadev. \u201cSurgical methods have been tried for more than 75 years, but all of these clinical trials have failed. Automation began with the availability of continuous glucose monitoring and algorithms to control insulin delivery. Although \u201cartificial pancreases\u201d have been available for 10 years, automation success has only been 40-60 percent,\u201d said Dr. Kesavadev.<\/p>\n<p>\n\n\n\n<\/p>\n<h2>Why are we Talking About Diabetes Treatments?<\/h2>\n<p>\n\n\n\n<\/p>\n<p>The cost of treating diabetes is similar to treating heart attacks. Kidney disease, strokes, neuropathy, blindness, amputations, mental illnesses, etc., all of which can be prevented by \u201cproper treatment of the underlying disease\u201d. \u201cThis is why such expensive devices are being made available free of charge in many countries, as they will prove extremely cost-effective in the long run,\u201d said Dr. published in&nbsp;<em>Therapeutic advances in endocrinology and metabolism<\/em>&nbsp;Magazine in October 2021.<\/p>\n<p>\n\n\n\n<\/p>\n<p>In the paper mention Dr. Kesavadev, Gopika Krishnan and Viswanathan Mohan, how the diabetes community uses various technologies such as connected glucose meters, continuous glucose monitoring systems, continuous subcutaneous insulin infusion, closed circuit systems, digitization of health data and diabetes-related apps to prevent and treat the condition.<\/p>\n<p>\n\n\n\n<\/p>\n<p>The WHO also states that for people with diabetes, access to affordable treatment, including insulin, is vital to their survival. \u201cThere is a globally agreed goal to halt the rise in diabetes and obesity by 2025,\u201d says the WHO website.<\/p>\n<p>\n\n\n\n<\/p>\n<p>In a previous interview with&nbsp;<em>indianexpress.com&nbsp;<\/em>Luke Coutinho, Holistic Lifestyle Coach \u2013 Integrative and Lifestyle Medicine and Founder of YouCare \u2013 All about YOU said that \u201cintegrating technology into diabetes management\u201d is an excellent step in changing the face of this epidemic in our country and the world .<\/p>\n<p>\n\n\n\n<\/p>\n<p>\u201cOne thing we are constantly reminded of through our daily practice is the fact that each of us is bio-individuals, not just in terms of genes, but also in the way our bodies respond to a particular one Food or a specific ingredient reacts. This is where technology like CGMS (Continuous Glucose Monitoring System) can help us personalize our approach and tailor it to a specific individual,\u201d he explained.<\/p>\n<p>\n\n\n\n<\/p>\n<h2>What Types of AP are There?<\/h2>\n<p>\n\n\n\n<\/p>\n<p>There are different types of artificial pancreatic systems, said Dr. Chandy<\/p>\n<p>\n\n\n\n<\/p>\n<p>They include:<\/p>\n<p>\n\n\n\n<\/p>\n<p><em>Threshold suspend and predictive suspend systems<\/em><\/p>\n<p>\n\n\n\n<\/p>\n<p>The Threshold Suspend and Predictive Suspend systems can temporarily halt or \u201csuspend\u201d insulin delivery when blood glucose levels drop.<\/p>\n<p>\n\n\n\n<\/p>\n<p><em>Threshold suspend system<\/em><\/p>\n<p>\n\n\n\n<\/p>\n<h2>What is AP\u2019s 780G?<\/h2>\n<p>\n\n\n\n<\/p>\n<p>780G is an advanced type of insulin pump that automatically monitors the insulin level to be delivered depending on food intake.<\/p>\n<p>\n\n\n\n<\/p>\n<p>\u201cThis is the first time that 780G has achieved 80 percent success in automation and many patients using it have had success with a time in range (glucose within normal range) greater than 90 percent in 24 hours\u201d, said Dr Kesavadev.<\/p>\n<p>\n\n\n\n<\/p>\n<p>according to Dr Kesavadev, 780G is an international product from the United States. \u201cSimilar technologies have not yet reached India. It\u2019s life-saving, especially for children with type 1 diabetes who struggle day and night to keep glucose levels in the right range,\u201d he said.<\/p>\n<p>\n\n\n\n<\/p>\n<h2>How Does 780G Work?<\/h2>\n<p>\n\n\n\n<\/p>\n<p>Dr Kesavadev, who along with Dr. Arun Shankar, Gopika Krishnan and Geethu Sanal used and trained 780G in a 26-year-old person with type 1 diabetes, said that 780G automatically increases the insulin dose when glucose levels rise, and the insulin dose is automatically reduced when the glucose trend is low. \u201cThis happens once every five minutes without user intervention. When the meal is related&nbsp;insulin dosage&nbsp;is insufficient, an automatic correction dose is also delivered. The results are amazing. In our first patient, glucose stays within the normal range more than 90 percent of the time. This is an incredible achievement,\u201d he said in a press statement.<\/p>\n<p>\n\n\n\n<\/p>\n<p>For his part, the user said: \u201cFor a number of reasons, I have not had a good night\u2019s sleep since my diabetes diagnosis for the past 16 years. The new automated insulin delivery device gives me restful sleep and has completely changed my life forever.\u201d<\/p>\n<p>\n\n\n\n<\/p>\n<h3>Factors to Consider Before Starting<\/h3>\n<p><b><br><\/b>1. Age \u2013 Some models are rated for ages 2+, while others are rated for ages 6+<br>2. Whether you can put the devices in the right position without help, check that they are working properly and adjust them if necessary, or enter carbohydrate data<br>3.Parents should consult with the child\u2019s doctor about appropriate artificial pancreatic systems.<br>4. How much does an artificial pancreas cost<\/p>\n<p>\n\n\n\n<\/p>\n<h3>Restrictions<\/h3>\n<p>\n\n\n\n<\/p>\n<p>Dr Chandy claims that AP systems are not completely hands off. \u201cThey have to regularly maintain the devices to make sure they\u2019re working properly and enter meal sizes into the system at each meal,\u201d he said.<\/p>\n<p>\n\n\n\n<\/p>\n<p><\/p>\n<h3>Too Check<\/h3>\n<p>1. Check the CGM and infusion pump catheters to ensure they are in place and replace if necessary<br>2. Check CGM for accuracy<\/p>\n<p>\n\n\n\n<\/p>\n<h3>Given These Factors, is it Still Promising?<\/h3>\n<p>\n\n\n\n<\/p>\n<p>Notably, the diabetes burden has increased globally, with India having the second-largest number in the world after China, with 77 million people with diabetes, according to a study by the Indian Council of Medical Research \u2013 India Diabetes (ICMR-INDIAB).<\/p>\n<p>\n\n\n\n<\/p>\n<p>AP has great potential to reduce the burden on diabetic patients in India, but the biggest challenge is cost, explained Dr. chandy \u201cThe most advanced system available in India would cost around six lakhs and the recurring monthly expenses would be around 12,000-15,000. Hopefully,&nbsp;Health insurance&nbsp;and reimbursement allows, the majority of people with type 1 diabetes could be using an artificial pancreas within the next five years,\u201d he said.<\/p>\n<p>\n\n\n\n<\/p>\n<p>Although very expensive, 780G is the only commercially available life-saving device in India, Dr. Kesavadev. \u201cIn order for more patients to benefit from this therapy, the government needs to make it available to them free of charge, especially for those aged 7 to 24 with diabetes,\u201d he said, sharing that he and his team are also \u201cdoing an AP for what should be much cheaper for the common man\u201d.<\/p>\n<p>\n\n\n\n<\/p>\n<p>Dr Kesavadev also pointed out that more doctors and nurses need to be trained to use this \u201csophisticated technology,\u201d without which insulin pump therapy typically fails. \u201cThe training will also help them identify suitable candidates and the type and level of training to be given to users and home caregivers.\u201d<\/p>\n<p>\n\n\n\n<\/p>\n<p>There may be errors and inaccuracies, and everyone may not understand how to use them, Dr. Moon pointed out. \u201cIt will take time for the people of India to become familiar with this technology. India has a rapidly growing diabetes population and many new methods have been introduced to help, but adaptation will take time,\u201d said Dr. Moon.<\/p>\n<p>\n\n\n\n<\/p>\n<p><strong>Dr. Pritam Moon, <br>Medical Specialist and Diabetologist, <br>Wockhardt Hospital Mira Road.<\/strong><\/p>\n<p>\n\n\n\n<\/p>\n<p>Source: <a href=\"https:\/\/newsbeezer.com\/india\/how-an-artificial-pancreas-can-be-crucial-for-diabetic-patients\/\">https:\/\/newsbeezer.com\/india\/how-an-artificial-pancreas-can-be-crucial-for-diabetic-patients\/<\/a><\/p>\n<p>\n","protected":false},"excerpt":{"rendered":"<p>The World Health Organization (WHO) describes&nbsp;Diabetes as a chronic metabolic disease&nbsp;characterized by elevated blood sugar levels (or&nbsp;blood sugar), which over time can cause severe damage to the heart, blood vessels,&nbsp;eyes, kidneys and nerves. It also states that approximately 422 million people worldwide have diabetes, most of whom live in low- and middle-income countries, and that <\/p>\n","protected":false},"author":2,"featured_media":51355,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[98],"tags":[],"class_list":["post-12212","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diabetes"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How an Artificial Pancreas Can Be Crucial for Diabetic Patients - International Wockhardt Hospitals<\/title>\n<meta name=\"description\" content=\"Artificial pancreas helps control blood sugar levels and makes it easier for people to keep them in range. 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